●In 1928, `color{Violet}"Frederick Griffith"`, in a series of experiments with `color{Violet}"𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘯𝘦𝘶𝘮𝘰𝘯𝘪𝘢𝘦"` (bacterium responsible for pneumonia), witnessed a miraculous transformation in the bacteria.
● During the course of his experiment, a `color{Violet}"living organism"` (bacteria) had `color{Violet}"changed"` in `color{Violet}"physical form"`.
● When 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘯𝘦𝘶𝘮𝘰𝘯𝘪𝘢𝘦 (pneumococcus) bacteria are grown on a culture plate, some produce `color{Violet}"smooth shiny"` colonies (`color{Violet}"S"`) while others produce `color{Violet}"rough colonies"` (`color{Violet}"R"`).
● This is because the S strain bacteria have a `color{Violet}"mucous (polysaccharide)"` coat, while R strain does not.
● Mice infected with the S strain (`color{Violet}"virulent"`) die from `color{Violet}"pneumonia infection"` but mice infected with the R strain `color{Violet}"do not"` develop pneumonia.
● Griffith was able to `color{Violet}"kill bacteria"` by `color{Violet}"heating"` them.
● He observed that `color{Violet}"heat-killed S strain"` bacteria injected into mice did not kill them.
● When he injected a `color{Violet}"mixture"` of `color{Violet}"heat-killed S"` and `color{Violet}"live R"` bacteria, the mice died.
● Moreover, he `color{Violet}"recovered"` `color{Violet}"living S"` bacteria from the `color{Violet}"dead mice"`.
● He concluded that the `color{Violet}"R strain"` bacteria had somehow been `color{Violet}"transformed"` by the `color{Violet}"heat-killed S strain"` bacteria.
● Some `color{blue}"transforming principle"`, transferred from the heat-killed S strain, had enabled the R strain to synthesise a `color{Violet}"smooth polysaccharide coat"` and become virulent.
● This must be due to the `color{Violet}"transfer"` of the `color{Violet}"genetic material"`.
● However, the `color{Violet}"biochemical nature"` of genetic material was `color{Violet}"not defined"` from his experiments.
●In 1928, `color{Violet}"Frederick Griffith"`, in a series of experiments with `color{Violet}"𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘯𝘦𝘶𝘮𝘰𝘯𝘪𝘢𝘦"` (bacterium responsible for pneumonia), witnessed a miraculous transformation in the bacteria.
● During the course of his experiment, a `color{Violet}"living organism"` (bacteria) had `color{Violet}"changed"` in `color{Violet}"physical form"`.
● When 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘯𝘦𝘶𝘮𝘰𝘯𝘪𝘢𝘦 (pneumococcus) bacteria are grown on a culture plate, some produce `color{Violet}"smooth shiny"` colonies (`color{Violet}"S"`) while others produce `color{Violet}"rough colonies"` (`color{Violet}"R"`).
● This is because the S strain bacteria have a `color{Violet}"mucous (polysaccharide)"` coat, while R strain does not.
● Mice infected with the S strain (`color{Violet}"virulent"`) die from `color{Violet}"pneumonia infection"` but mice infected with the R strain `color{Violet}"do not"` develop pneumonia.
● Griffith was able to `color{Violet}"kill bacteria"` by `color{Violet}"heating"` them.
● He observed that `color{Violet}"heat-killed S strain"` bacteria injected into mice did not kill them.
● When he injected a `color{Violet}"mixture"` of `color{Violet}"heat-killed S"` and `color{Violet}"live R"` bacteria, the mice died.
● Moreover, he `color{Violet}"recovered"` `color{Violet}"living S"` bacteria from the `color{Violet}"dead mice"`.
● He concluded that the `color{Violet}"R strain"` bacteria had somehow been `color{Violet}"transformed"` by the `color{Violet}"heat-killed S strain"` bacteria.
● Some `color{blue}"transforming principle"`, transferred from the heat-killed S strain, had enabled the R strain to synthesise a `color{Violet}"smooth polysaccharide coat"` and become virulent.
● This must be due to the `color{Violet}"transfer"` of the `color{Violet}"genetic material"`.
● However, the `color{Violet}"biochemical nature"` of genetic material was `color{Violet}"not defined"` from his experiments.
